2.21 Xenogenic tissues and biomaterials for the skeletal system

V. Graceffa, Z. Wu, D. Gaspar, K. Spanoudes, I. L.M. Isa, M. Biggs, A. M. Mullen, A. Pandit, D. I. Zeugolis

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Musculoskeletal injuries and degenerative conditions constitute a bottleneck to the healthcare system. Tissue grafts and scaffolds based on extracellular matrix molecules have received much attention since they closely imitate the structural, biochemical, biophysical and biological properties of the tissue to be replaced. This review summarises the most abundant extracellular matrix components that are used in tissue engineering applications for bone, intervertebral disc, cartilage and tendon.

Original languageEnglish
Title of host publicationComprehensive Biomaterials II
PublisherElsevier
Pages471-504
Number of pages34
ISBN (Electronic)9780081006924
ISBN (Print)9780081006917
DOIs
Publication statusPublished - 1 Jan 2017
Externally publishedYes

Keywords

  • Bone regeneration
  • Cartilage regeneration
  • Collagen
  • Elastin
  • Fibronectin
  • Glycosaminoglycans
  • Growth factors
  • Intervertebral disc regeneration
  • Laminin
  • Proteoglycans
  • Stem cells
  • Tendon regeneration
  • Tissue grafts

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