TY - JOUR
T1 - Colloidal Photonic Crystal-Enhanced Fluorescence of Gold Nanoclusters
T2 - A Highly Sensitive Solid-state Fluorescent Probe for Creatinine
AU - Thomas, Meghana Mary
AU - Babu, Aswathy
AU - Chandran, Parvathy R.
AU - Silpa T, S.
AU - Pillai, Saju
N1 - Publisher Copyright:
© 2022 Wiley-VCH GmbH.
PY - 2023/1/17
Y1 - 2023/1/17
N2 - Gold nanoclusters (AuNCs) are an intensely pursued class of fluorophores with excellent biocompatibility, high water solubility, and ease of further conjugation. However, their low quantum yield limits their applications, such as ultra-sensitive chemical or molecular sensing. To address this problem, various strategies have been adopted for augmenting their fluorescence intensity. Herein, we report a facile and scalable approach for the fluorescence enhancement of bovine serum albumin (BSA) capped AuNCs (BSA-AuNCs) using periodic, close-packed polystyrene colloidal photonic crystals (CPCs). The slow photon effect at the bandgap edges is utilized for the increased light-matter interactions and thereby enhancing the fluorescence intensity of the BSA-AuNCs. Compared to the planar polystyrene control sample, the CPC film yielded a 14-fold enhancement in fluorescence intensity. Further, we demonstrated the as-prepared BSA-AuNCs-CPC as a solid-state platform for the highly sensitive and selective fluorescence turn-off detection of creatinine at nanomolar level.
AB - Gold nanoclusters (AuNCs) are an intensely pursued class of fluorophores with excellent biocompatibility, high water solubility, and ease of further conjugation. However, their low quantum yield limits their applications, such as ultra-sensitive chemical or molecular sensing. To address this problem, various strategies have been adopted for augmenting their fluorescence intensity. Herein, we report a facile and scalable approach for the fluorescence enhancement of bovine serum albumin (BSA) capped AuNCs (BSA-AuNCs) using periodic, close-packed polystyrene colloidal photonic crystals (CPCs). The slow photon effect at the bandgap edges is utilized for the increased light-matter interactions and thereby enhancing the fluorescence intensity of the BSA-AuNCs. Compared to the planar polystyrene control sample, the CPC film yielded a 14-fold enhancement in fluorescence intensity. Further, we demonstrated the as-prepared BSA-AuNCs-CPC as a solid-state platform for the highly sensitive and selective fluorescence turn-off detection of creatinine at nanomolar level.
KW - Au-BSA
KW - colloidal photonic crystal
KW - creatinine detection
KW - fluorescence enhancement
KW - photonic band gap
UR - http://www.scopus.com/inward/record.url?scp=85144999209&partnerID=8YFLogxK
U2 - 10.1002/asia.202201035
DO - 10.1002/asia.202201035
M3 - Article
C2 - 36519438
AN - SCOPUS:85144999209
SN - 1861-4728
VL - 18
JO - Chemistry - An Asian Journal
JF - Chemistry - An Asian Journal
IS - 2
M1 - e202201035
ER -