@inproceedings{be3846915dd94444ab52316c2ca8bc2f,
title = "Fabry-P{\'e}rot based refractive index optical fiber sensor for measurement of oxygen concentration levels in hypoxic tumors during radiotherapy treatment",
abstract = "An optical fiber sensor based on Fabry-P{\'e}rot interferometer to measure the refractive index changes due to oxygenation level changes in hypoxic tumors for radiotherapy treatments is proposed. The sensors have an outer diameter of 220μm with a 20-30μm length air-cavity and a 30μm thickness end cap located at the tip of the sensor. The sensors are used to measure the phase change in the received optical spectrum when there is a change in refractive index using a Fast Fourier Transform based analysis method. The refractive index change is measured in order to determine the oxygenation level in hypoxic tumors. In this paper, different concentrations of iso-propanol solution are prepared to produce refractive index values between 1.3438 and 1.3655 in order to mimic the refractive index of hemoglobin. The sensors are coated with a 100 nm thick gold layer and a comparison is made with non-coated sensors. The coated sensors have a resolution in order of 10-3 RIU.",
keywords = "Fabry-P{\'e}rot interferometer, Hypoxic tumors, Refractive index sensors",
author = "Charusluk Viphavakit and Dineshbabu Duraibabu and Sinead O'Keeffe and Elfed Lewis",
note = "Publisher Copyright: {\textcopyright} 2017 SPIE.; 25th International Conference on Optical Fiber Sensors, OFS 2017 ; Conference date: 24-04-2017 Through 28-04-2017",
year = "2017",
doi = "10.1117/12.2265084",
language = "English",
series = "Proceedings of SPIE - The International Society for Optical Engineering",
publisher = "SPIE",
editor = "Libo Yuan and Youngjoo Chung and Wei Jin and Byoungho Lee and John Canning and Kentaro Nakamura",
booktitle = "25th International Conference on Optical Fiber Sensors",
}