TY - GEN
T1 - Fiber-optic technologies for advanced thermo-therapy applied ex vivo to liver tumors
AU - Tosi, D.
AU - Perrone, G.
AU - Vallan, A.
AU - Braglia, A.
AU - Liu, Y.
AU - Macchi, E. G.
AU - Braschi, G.
AU - Gallati, M.
AU - Cigada, A.
AU - Poeggel, S.
AU - Duraibabu, D. B.
AU - Leen, G.
AU - Lewis, E.
N1 - Publisher Copyright:
© 2015 SPIE-OSA.
PY - 2015
Y1 - 2015
N2 - Thermal ablation, using radiofrequency, microwave, and laser sources, is a common treatment for hepatic tumors. Sensors allow monitoring, at the point of treatment, the evolution of thermal ablation procedures. We present optical fiber sensors that allow advanced capabilities for recording the biophysical phenomena occurring in the tissue in real time. Distributed or quasi-distributed thermal sensors allow recording temperature with spatial resolution ranging from 0.1 mm to 5 mm. In addition, a thermally insensitive pressure sensor allows recording pressure rise, supporting advanced treatment of encapsulated tumors. Our investigation is focused on two case studies: (1) radiofrequency ablation of hepatic tissue, performed on a phantom with a stem-shaped applicator; (2) laser ablation of a liver phantom, performed with a fiber laser. The main measurement results are discussed, comparing the technologies used for the investigation, and drawing the potential for using optical fiber sensors for "smart"-ablation.
AB - Thermal ablation, using radiofrequency, microwave, and laser sources, is a common treatment for hepatic tumors. Sensors allow monitoring, at the point of treatment, the evolution of thermal ablation procedures. We present optical fiber sensors that allow advanced capabilities for recording the biophysical phenomena occurring in the tissue in real time. Distributed or quasi-distributed thermal sensors allow recording temperature with spatial resolution ranging from 0.1 mm to 5 mm. In addition, a thermally insensitive pressure sensor allows recording pressure rise, supporting advanced treatment of encapsulated tumors. Our investigation is focused on two case studies: (1) radiofrequency ablation of hepatic tissue, performed on a phantom with a stem-shaped applicator; (2) laser ablation of a liver phantom, performed with a fiber laser. The main measurement results are discussed, comparing the technologies used for the investigation, and drawing the potential for using optical fiber sensors for "smart"-ablation.
KW - Interventional cancer care
KW - Liver tumor ablation
KW - Optical fiber sensors (OFS)
KW - Thermal ablation
KW - Thermo-therapy
UR - http://www.scopus.com/inward/record.url?scp=85165793291&partnerID=8YFLogxK
U2 - 10.1117/12.2181200
DO - 10.1117/12.2181200
M3 - Conference contribution
AN - SCOPUS:85165793291
SN - 9781628417012
T3 - Optics InfoBase Conference Papers
BT - European Conference on Biomedical Optics, ECBO 2015
PB - Optica Publishing Group (formerly OSA)
T2 - European Conference on Biomedical Optics, ECBO 2015
Y2 - 21 June 2015 through 25 June 2015
ER -