Fiber-optic technologies for advanced thermo-therapy applied ex vivo to liver tumors

D. Tosi, G. Perrone, A. Vallan, A. Braglia, Y. Liu, E. G. Macchi, G. Braschi, M. Gallati, A. Cigada, S. Poeggel, D. B. Duraibabu, G. Leen, E. Lewis

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Thermal ablation, using radiofrequency, microwave, and laser sources, is a common treatment for hepatic tumors. Sensors allow monitoring, at the point of treatment, the evolution of thermal ablation procedures. We present optical fiber sensors that allow advanced capabilities for recording the biophysical phenomena occurring in the tissue in real time. Distributed or quasi-distributed thermal sensors allow recording temperature with spatial resolution ranging from 0.1 mm to 5 mm. In addition, a thermally insensitive pressure sensor allows recording pressure rise, supporting advanced treatment of encapsulated tumors. Our investigation is focused on two case studies: (1) radiofrequency ablation of hepatic tissue, performed on a phantom with a stem-shaped applicator; (2) laser ablation of a liver phantom, performed with a fiber laser. The main measurement results are discussed, comparing the technologies used for the investigation, and drawing the potential for using optical fiber sensors for "smart"-ablation.

Original languageEnglish
Title of host publicationEuropean Conference on Biomedical Optics, ECBO 2015
PublisherOptica Publishing Group (formerly OSA)
ISBN (Print)9781628417012
DOIs
Publication statusPublished - 2015
Externally publishedYes
EventEuropean Conference on Biomedical Optics, ECBO 2015 - Munich, Germany
Duration: 21 Jun 201525 Jun 2015

Publication series

NameOptics InfoBase Conference Papers
ISSN (Electronic)2162-2701

Conference

ConferenceEuropean Conference on Biomedical Optics, ECBO 2015
Country/TerritoryGermany
CityMunich
Period21/06/1525/06/15

Keywords

  • Interventional cancer care
  • Liver tumor ablation
  • Optical fiber sensors (OFS)
  • Thermal ablation
  • Thermo-therapy

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