FLAK: Ultra-fast fuzzy whole genome alignment

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Citation (Scopus)

Abstract

The advent of high throughput DNA sequencing has lead to the availability of a rapidly growing number of genomes of complete or draft quality. Whole genome alignment has consequently become an increasingly important field in bioinformatics. This paper describes a novel approach for comparing two whole genomes based on fuzzy logic. Benchmarks against pre-eminent whole genome alignment systems have demonstrated that the fuzzy approach outperforms existing systems in the context of alignment times and enables analyses that are not possible with other approaches.

Original languageEnglish
Title of host publication10th International Conference on Practical Applications of Computational Biology and Bioinformatics
EditorsFlorentino Fdez-Riverola, Juan F. De Paz, Miguel P. Rocha, Francisco J. Domínguez Mayo, Mohd Saberi Mohamad
PublisherSpringer Verlag
Pages123-131
Number of pages9
ISBN (Print)9783319401256
DOIs
Publication statusPublished - 2016
EventInternational Conference on Practical Applications of Computational Biology and Bioinformatics PACBB, 2016 - Sevilla, Spain
Duration: 1 Jun 20163 Jun 2016

Publication series

NameAdvances in Intelligent Systems and Computing
Volume477
ISSN (Print)2194-5357

Conference

ConferenceInternational Conference on Practical Applications of Computational Biology and Bioinformatics PACBB, 2016
Country/TerritorySpain
CitySevilla
Period1/06/163/06/16

Keywords

  • Fuzzy
  • Hedges
  • K-mer
  • Rapid
  • Whole genome alignment

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