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FLAK: Ultra-fast fuzzy whole genome alignment

    Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

    1 Citation (Scopus)

    Abstract

    The advent of high throughput DNA sequencing has lead to the availability of a rapidly growing number of genomes of complete or draft quality. Whole genome alignment has consequently become an increasingly important field in bioinformatics. This paper describes a novel approach for comparing two whole genomes based on fuzzy logic. Benchmarks against pre-eminent whole genome alignment systems have demonstrated that the fuzzy approach outperforms existing systems in the context of alignment times and enables analyses that are not possible with other approaches.

    Original languageEnglish
    Title of host publication10th International Conference on Practical Applications of Computational Biology and Bioinformatics
    EditorsFlorentino Fdez-Riverola, Juan F. De Paz, Miguel P. Rocha, Francisco J. Domínguez Mayo, Mohd Saberi Mohamad
    PublisherSpringer Verlag
    Pages123-131
    Number of pages9
    ISBN (Print)9783319401256
    DOIs
    Publication statusPublished - 2016
    EventInternational Conference on Practical Applications of Computational Biology and Bioinformatics PACBB, 2016 - Sevilla, Spain
    Duration: 1 Jun 2016 → 3 Jun 2016

    Publication series

    NameAdvances in Intelligent Systems and Computing
    Volume477
    ISSN (Print)2194-5357

    Conference

    ConferenceInternational Conference on Practical Applications of Computational Biology and Bioinformatics PACBB, 2016
    Country/TerritorySpain
    CitySevilla
    Period1/06/16 → 3/06/16

    Keywords

    • Fuzzy
    • Hedges
    • K-mer
    • Rapid
    • Whole genome alignment

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