Gene Expression Analysis by Reverse Transcription Quantitative PCR

Eva M. Campion, Sinéad T. Loughran

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

1 Citation (Scopus)

Abstract

The reverse transcription quantitative polymerase chain reaction (RT-qPCR) is a rapid detection technology that allows the amplification and quantification of specific RNA transcripts. RT-qPCR has increasingly been adopted for the detection and quantification of H. pylori across a range of sample types and applications. In addition, it is widely used to monitor host gene expression in cells and tissues in response to H. pylori infection. Outlined here is a two-step protocol that can be employed to analyze gene expression in H. pylori or H. pylori-infected samples.

Original languageEnglish
Title of host publicationMethods in Molecular Biology
PublisherHumana Press Inc.
Pages61-74
Number of pages14
DOIs
Publication statusPublished - 2021

Publication series

NameMethods in Molecular Biology
Volume2283
ISSN (Print)1064-3745
ISSN (Electronic)1940-6029

Keywords

  • RNA
  • Real-time PCR
  • Relative quantification
  • Reverse transcription
  • cDNA

Fingerprint

Dive into the research topics of 'Gene Expression Analysis by Reverse Transcription Quantitative PCR'. Together they form a unique fingerprint.

Cite this