TY - JOUR
T1 - Mining marine shellfish wastes for bioactive molecules
T2 - Chitin and chitosan - Part B: Applications
AU - Hayes, Maria
AU - Carney, Brian
AU - Slater, John
AU - Brück, Wolfram
PY - 2008/7
Y1 - 2008/7
N2 - Due to their unique chemical characteristics (including biodegradability to non-toxic products, physiological inertness and hydrophilicity), chitin, chitosan and their derivatives may be expansively utilized in the biotechnological, agricultural, food protection and nutraceutical, medicinal and pharmacological fields and in the areas of bioremediation and genetherapy. Biological actions associated with chitin and shell waste by-products include among others antibacterial, angiotensin-1-converting enzyme-inhibitory and immunomodulatory activities, while the chitinolytic microbes and enzymes associated with chitinolysis also play a role in the de novo generation of further bioactivites. In Part B of this review we relate in more detail some of the bioactivities and applications of chitin and shell waste by-products.
AB - Due to their unique chemical characteristics (including biodegradability to non-toxic products, physiological inertness and hydrophilicity), chitin, chitosan and their derivatives may be expansively utilized in the biotechnological, agricultural, food protection and nutraceutical, medicinal and pharmacological fields and in the areas of bioremediation and genetherapy. Biological actions associated with chitin and shell waste by-products include among others antibacterial, angiotensin-1-converting enzyme-inhibitory and immunomodulatory activities, while the chitinolytic microbes and enzymes associated with chitinolysis also play a role in the de novo generation of further bioactivites. In Part B of this review we relate in more detail some of the bioactivities and applications of chitin and shell waste by-products.
KW - ACE-inhibitory
KW - Antimicrobial
KW - Chitin oligosaccharides
KW - Immunomodulation
UR - http://www.scopus.com/inward/record.url?scp=48749132863&partnerID=8YFLogxK
U2 - 10.1002/biot.200800027
DO - 10.1002/biot.200800027
M3 - Review article
C2 - 18320569
AN - SCOPUS:48749132863
SN - 1860-6768
VL - 3
SP - 878
EP - 889
JO - Biotechnology Journal
JF - Biotechnology Journal
IS - 7
ER -