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Polysaccharides—Naturally Occurring Immune Modulators

  • Emma J. Murphy
  • , Gustavo Waltzer Fehrenbach
  • , Ismin Zainol Abidin
  • , Ciara Buckley
  • , Therese Montgomery
  • , Robert Pogue
  • , Patrick Murray
  • , Ian Major
  • , Emanuele Rezoagli
  • Technological University of the Shannon (TUS)
  • Universidade Católica de Brasilia
  • Fondazione IRCCS San Gerardo dei Tintori
  • University of Milan - Bicocca

Research output: Contribution to journalReview articlepeer-review

121 Citations (Scopus)

Abstract

The prevention of disease and infection requires immune systems that operate effectively. This is accomplished by the elimination of infections and abnormal cells. Immune or biological therapy treats disease by either stimulating or inhibiting the immune system, dependent upon the circumstances. In plants, animals, and microbes, polysaccharides are abundant biomacromolecules. Due to the intricacy of their structure, polysaccharides may interact with and impact the immune response; hence, they play a crucial role in the treatment of several human illnesses. There is an urgent need for the identification of natural biomolecules that may prevent infection and treat chronic disease. This article addresses some of the naturally occurring polysaccharides of known therapeutic potential that have already been identified. This article also discusses extraction methods and immunological modulatory capabilities.

Original languageEnglish
Article number2373
JournalPolymers
Volume15
Issue number10
DOIs
Publication statusPublished - May 2023

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • immune modulation
  • inflammation
  • naturally occurring polymers
  • polysaccharides

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