Sinapinic and protocatechuic acids found in rapeseed: Isolation, characterisation and potential benefits for human health as functional food ingredients

Leah Quinn, Steven G. Gray, Steven Meaney, Stephen Finn, Owen Kenny, Maria Hayes

Research output: Contribution to journalReview articlepeer-review

21 Citations (Scopus)

Abstract

Rapeseed is one of the world’s major oilseeds, and rapeseed oil is produced by pressing of the seeds. This process results in the production of a low-economic-value by-product, rapeseed meal, which is commonly used as animal feed. Rapeseed meal is rich in bioactive phenolic compounds, including sinapinic acid (SA) and protocatechuic acid (PCA). Isolation of these bioactive compounds from a by-product of rapeseed oil production is largely in agreement with the current concept of the circular economy and total utilisation of crop harvest using a biorefinery approach. In this review, current information concerning traditional and novel methods to isolate phenolic compounds – including SA and PCA – from rapeseed meal, along with in vitro and in vivo studies concerning the bioactivity of SA and PCA and their associated health effects, is collated. These health effects include anti-inflammatory, anti-cancer, anti-diabetes activities, along with histone deacetylase inhibition and protective cardiovascular, neurological and hepatic effects. The traditional extraction methods include use of solvents and/or enzymes. However, a need for simpler, more efficient methodologies has led to the development of novel extraction processes, including microwave-assisted, ultrasound-assisted, pulsed electric field and high-voltage electrical discharge extraction processes.

Original languageEnglish
Pages (from-to)104-119
Number of pages16
JournalIrish Journal of Agricultural and Food Research
Volume56
Issue number1
DOIs
Publication statusPublished - 2017
Externally publishedYes

Keywords

  • Cardiovascular health
  • Diabetes
  • Protocatechuic and sinapinic acid

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