TY - JOUR
T1 - Sinapinic and protocatechuic acids found in rapeseed
T2 - Isolation, characterisation and potential benefits for human health as functional food ingredients
AU - Quinn, Leah
AU - Gray, Steven G.
AU - Meaney, Steven
AU - Finn, Stephen
AU - Kenny, Owen
AU - Hayes, Maria
N1 - Publisher Copyright:
© 2017, Sciendo. All rights reserved.
PY - 2017
Y1 - 2017
N2 - Rapeseed is one of the world’s major oilseeds, and rapeseed oil is produced by pressing of the seeds. This process results in the production of a low-economic-value by-product, rapeseed meal, which is commonly used as animal feed. Rapeseed meal is rich in bioactive phenolic compounds, including sinapinic acid (SA) and protocatechuic acid (PCA). Isolation of these bioactive compounds from a by-product of rapeseed oil production is largely in agreement with the current concept of the circular economy and total utilisation of crop harvest using a biorefinery approach. In this review, current information concerning traditional and novel methods to isolate phenolic compounds – including SA and PCA – from rapeseed meal, along with in vitro and in vivo studies concerning the bioactivity of SA and PCA and their associated health effects, is collated. These health effects include anti-inflammatory, anti-cancer, anti-diabetes activities, along with histone deacetylase inhibition and protective cardiovascular, neurological and hepatic effects. The traditional extraction methods include use of solvents and/or enzymes. However, a need for simpler, more efficient methodologies has led to the development of novel extraction processes, including microwave-assisted, ultrasound-assisted, pulsed electric field and high-voltage electrical discharge extraction processes.
AB - Rapeseed is one of the world’s major oilseeds, and rapeseed oil is produced by pressing of the seeds. This process results in the production of a low-economic-value by-product, rapeseed meal, which is commonly used as animal feed. Rapeseed meal is rich in bioactive phenolic compounds, including sinapinic acid (SA) and protocatechuic acid (PCA). Isolation of these bioactive compounds from a by-product of rapeseed oil production is largely in agreement with the current concept of the circular economy and total utilisation of crop harvest using a biorefinery approach. In this review, current information concerning traditional and novel methods to isolate phenolic compounds – including SA and PCA – from rapeseed meal, along with in vitro and in vivo studies concerning the bioactivity of SA and PCA and their associated health effects, is collated. These health effects include anti-inflammatory, anti-cancer, anti-diabetes activities, along with histone deacetylase inhibition and protective cardiovascular, neurological and hepatic effects. The traditional extraction methods include use of solvents and/or enzymes. However, a need for simpler, more efficient methodologies has led to the development of novel extraction processes, including microwave-assisted, ultrasound-assisted, pulsed electric field and high-voltage electrical discharge extraction processes.
KW - Cardiovascular health
KW - Diabetes
KW - Protocatechuic and sinapinic acid
UR - http://www.scopus.com/inward/record.url?scp=85055210278&partnerID=8YFLogxK
U2 - 10.1515/IJAFR-2017-0012
DO - 10.1515/IJAFR-2017-0012
M3 - Review article
AN - SCOPUS:85055210278
SN - 0791-6833
VL - 56
SP - 104
EP - 119
JO - Irish Journal of Agricultural and Food Research
JF - Irish Journal of Agricultural and Food Research
IS - 1
ER -