TY - JOUR
T1 - Whole blood thallium determination by GFAAS with high-frequency modulation polarization Zeeman effect background correction
AU - Solovyev, Nikolay D.
AU - Ivanenko, Natalya B.
AU - Ivanenko, Anatoly A.
PY - 2011/10
Y1 - 2011/10
N2 - A new technique of blood thallium direct determination based on graphite furnace atomic absorption spectrometry with Zeeman background absorption correction system was designed. The developed technique does not require sample digestion. Sample treatment includes only a fivefold per volume dilution of blood sample with 0.1% (m/v) Triton X-100. L'vov integrated platform was modified with 400 μg of Rh. Matrix modifier (200 μg NH4NO 3 and 160 μg Pd(NO3)2) was suggested for coping chloride and blood organic matter interferences. Standard reference material (Clincheck® Plasma Control for trace elements) analysis was used for validation. Additional validation was performed by analyzing spiked blood samples in the whole dynamic range. The dynamic range was 2-50 μg/L. Precision (RSD) was found <12%. Blood thallium limit of detection was 0.2 μg/L.
AB - A new technique of blood thallium direct determination based on graphite furnace atomic absorption spectrometry with Zeeman background absorption correction system was designed. The developed technique does not require sample digestion. Sample treatment includes only a fivefold per volume dilution of blood sample with 0.1% (m/v) Triton X-100. L'vov integrated platform was modified with 400 μg of Rh. Matrix modifier (200 μg NH4NO 3 and 160 μg Pd(NO3)2) was suggested for coping chloride and blood organic matter interferences. Standard reference material (Clincheck® Plasma Control for trace elements) analysis was used for validation. Additional validation was performed by analyzing spiked blood samples in the whole dynamic range. The dynamic range was 2-50 μg/L. Precision (RSD) was found <12%. Blood thallium limit of detection was 0.2 μg/L.
KW - Blood analysis
KW - Graphite furnace atomic absorption spectrometry
KW - Modifiers in GFAAS
KW - Thallium
KW - Trace element
UR - http://www.scopus.com/inward/record.url?scp=80054748800&partnerID=8YFLogxK
U2 - 10.1007/s12011-010-8865-0
DO - 10.1007/s12011-010-8865-0
M3 - Article
C2 - 20922499
AN - SCOPUS:80054748800
SN - 0163-4984
VL - 143
SP - 591
EP - 599
JO - Biological Trace Element Research
JF - Biological Trace Element Research
IS - 1
ER -